When a top-secret weapon falls into mercenary hands, wild card CIA agent Mason Mace Brown (Oscar-nominated actress Jessica Chastain) will need to join forces with rival badass German agent Marie (Diane Kruger), former MI6 ally and cutting-edge computer specialist Khadijah (Oscar winner Lupita Nyongo), and skilled Colombian psychologist Graciela (Penelope Cruz) on a lethal, breakneck mission to retrieve it, while also staying one-step ahead of a mysterious woman, Lin Mi Sheng (Bingbing Fan), who is tracking their every move. As the action rockets around the globe from the cafes of Paris to the markets of Morocco to the wealth and glamour of Shanghai, the quartet of women will forge a tenuous loyalty that could protect the world - or get them killed.